Fine pathogen discrimination within the APL1 gene family protects Anopheles gambiae against human and rodent malaria species.

Fine pathogen discrimination within the APL1 gene family protects Anopheles gambiae against human and rodent malaria species.

Genetically controlled resistance of Anopheles gambiae mosquitoes to Plasmodium falciparum is a common trait in the natural population, and a cluster of natural resistance loci were mapped to the Plasmodium-Resistance Island (PRI) of the A. gambiae genome. The APL1 family of leucine-rich repeat (LRR...

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Bibliographic Details
Main Authors:	Christian Mitri, Jean-Claude Jacques, Isabelle Thiery, Michelle M Riehle, Jiannong Xu, Emmanuel Bischoff, Isabelle Morlais, Sandrine E Nsango, Kenneth D Vernick, Catherine Bourgouin
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2009-09-01
Series:	PLoS Pathogens
Online Access:	http://europepmc.org/articles/PMC2734057?pdf=render

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