Proving Nanoscale Chiral Interactions of Cyclodextrins and Propranolol Enantiomers by Means of SERS Measurements Performed on a Solid Plasmonic Substrate

Proving Nanoscale Chiral Interactions of Cyclodextrins and Propranolol Enantiomers by Means of SERS Measurements Performed on a Solid Plasmonic Substrate

Chiral separation is an important issue for the pharmaceutical industry. Over the years, several separation methods have been developed, mainly based on chromatography. Their working principle is based on the formation of transient diastereoisomers, but the very subtle nanoscale interactions respons...

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Bibliographic Details
Main Authors: Gabriela Fabiola Știufiuc, Valentin Toma, Anca Onaciu, Vasile Chiș, Constantin Mihai Lucaciu, Rareș Ionuț Știufiuc
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Pharmaceutics
Subjects:
cyclodextrins
chiral interactions
Raman
SERS
quantum calculations
Online Access:https://www.mdpi.com/1999-4923/13/10/1594

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https://www.mdpi.com/1999-4923/13/10/1594

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