Critical role of glycogen synthase kinase-3β in regulating the avian heterophil response to Salmonella enterica serovar Enteritidis

Critical role of glycogen synthase kinase-3β in regulating the avian heterophil response to Salmonella enterica serovar Enteritidis

A microarray-assisted gene expression screen of chicken heterophils revealed glycogen synthase kinase-3β (GSK-3β), a multifunctional Ser/Thr kinase, to be consistently up-regulated 30-180 min following stimulation with Salmonella enterica serovar Enteritidis (S. Enteritidis). The present study was...

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Bibliographic Details
Main Authors: Michael eKogut, Christina L Swaggerty, Hsin I Chiang, Kenneth James Genovese, Haiqi eHe, Huaijun eZhou, Ryan eArsenault
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Veterinary Science
Subjects:
Chickens
Salmonella
innate immunity
heterophils
glycogen synthase kinase-3β
Online Access:http://journal.frontiersin.org/Journal/10.3389/fvets.2014.00010/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fvets.2014.00010/full

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