RNA sequencing reveals the expression profiles of circRNA and indicates that circDDX17 acts as a tumor suppressor in colorectal cancer

RNA sequencing reveals the expression profiles of circRNA and indicates that circDDX17 acts as a tumor suppressor in colorectal cancer

Abstract Background Circular RNA (circRNA) is a novel class of noncoding RNAs with functions in various pathophysiological activities. However, the expression profiles and functions of circRNAs in colorectal cancer (CRC) remain largely unknown. Methods High-throughput RNA sequencing (RNA-seq) was pe...

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Bibliographic Details
Main Authors: Xiang-Nan Li, Zhen-Jun Wang, Chun-Xiang Ye, Bao-Cheng Zhao, Zhu-Lin Li, Yong Yang
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Colorectal cancer
Circular RNAs
High-throughput sequencing
Bioinformatic analysis
CircDDX17
Tumor suppressor
Online Access:http://link.springer.com/article/10.1186/s13046-018-1006-x

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http://link.springer.com/article/10.1186/s13046-018-1006-x

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