Duplicated leptin receptors in two species of eel bring new insights into the evolution of the leptin system in vertebrates.

Since its discovery in mammals as a key-hormone in reproduction and metabolism, leptin has been identified in an increasing number of tetrapods and teleosts. Tetrapods possess only one leptin gene, while most teleosts possess two leptin genes, as a result of the teleost third whole genome duplicatio...

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Bibliographic Details
Main Authors: Marina Morini, Jérémy Pasquier, Ron Dirks, Guido van den Thillart, Jonna Tomkiewicz, Karine Rousseau, Sylvie Dufour, Anne-Gaëlle Lafont
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0126008