Cell-Free Hemoglobin Does Not Attenuate the Effects of SARS-CoV-2 Spike Protein S1 Subunit in Pulmonary Endothelial Cells

Cell-Free Hemoglobin Does Not Attenuate the Effects of SARS-CoV-2 Spike Protein S1 Subunit in Pulmonary Endothelial Cells

SARS-CoV-2 primarily infects epithelial airway cells that express the host entry receptor angiotensin-converting enzyme 2 (ACE2), which binds to the S1 spike protein on the surface of the virus. To delineate the impact of S1 spike protein interaction with the ACE2 receptor, we incubated the S1 spike...

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Bibliographic Details
Main Authors: Sirsendu Jana, Michael R. Heaven, Abdu I. Alayash
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
COVID-19
spike protein
endothelium
bioenergetics
proteomics
Online Access:https://www.mdpi.com/1422-0067/22/16/9041

Internet

https://www.mdpi.com/1422-0067/22/16/9041

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