A Hepatic GAbp-AMPK Axis Links Inflammatory Signaling to Systemic Vascular Damage

A Hepatic GAbp-AMPK Axis Links Inflammatory Signaling to Systemic Vascular Damage

Increased pro-inflammatory signaling is a hallmark of metabolic dysfunction in obesity and diabetes. Although both inflammatory and energy substrate handling processes represent critical layers of metabolic control, their molecular integration sites remain largely unknown. Here, we identify the hete...

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Bibliographic Details
Main Authors: Katharina Niopek, Bilgen Ekim Üstünel, Susanne Seitz, Minako Sakurai, Annika Zota, Frits Mattijssen, Xiaoyue Wang, Tjeerd Sijmonsma, Yvonne Feuchter, Anna M. Gail, Barbara Leuchs, Dominik Niopek, Oskar Staufer, Maik Brune, Carsten Sticht, Norbert Gretz, Karin Müller-Decker, Hans-Peter Hammes, Peter Nawroth, Thomas Fleming, Michael D. Conkright, Matthias Blüher, Anja Zeigerer, Stephan Herzig, Mauricio Berriel Diaz
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Cell Reports
Subjects:
GAbp
AMPK
liver
atherogenesis
TNF-α
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717309890

Internet

http://www.sciencedirect.com/science/article/pii/S2211124717309890

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