Regulatory T cells: serious contenders in the promise for immunological tolerance in transplantation

Regulatory T cells: serious contenders in the promise for immunological tolerance in transplantation

Regulatory T cells (Tregs) play an important role in immunoregulation and have been shown in animal models to promote transplantation tolerance and curb autoimmunity following their adoptive transfer. The safety and potential therapeutic efficacy of these cells has already been reported in Phase I t...

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Bibliographic Details
Main Authors: Niloufar eSafinia, Cristiano eScotta, Trishan eVaikunthanathan, Robert Ian Lechler, Giovanna eLombardi
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-08-01
Series:Frontiers in Immunology
Subjects:
Transplantation
tolerance
clinical trials
cellular therapy
Tregs
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00438/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00438/full

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