A pro-oxidant combination of resveratrol and copper down-regulates hallmarks of cancer and immune checkpoints in patients with advanced oral cancer: Results of an exploratory study (RESCU 004)

BackgroundOur earlier studies have shown that cell-free chromatin particles (cfChPs) that are released from dying cancer cells are readily internalised by bystander cells leading to activation of two hallmarks of cancer viz. genome instability and inflammation. These hallmarks could be down-regulate...

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Main Authors: Aishwarya Pilankar, Hitesh Singhavi, Gorantla V. Raghuram, Sophiya Siddiqui, Naveen Kumar Khare, Vishalkumar Jadhav, Harshali Tandel, Kavita Pal, Atanu Bhattacharjee, Pankaj Chaturvedi, Indraneel Mittra
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1000957/full