Piggybacking on Classical Import and Other Non-Classical Mechanisms of Nuclear Import Appear Highly Prevalent within the Human Proteome

One of the most conserved cellular pathways among eukaryotes is the extensively studied classical protein nuclear import pathway mediated by importin-α. Classical nuclear localization signals (cNLSs) are recognized by importin-α and are highly predictable due to their abundance of basic amino acids....

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Bibliographic Details
Main Authors: Tanner M. Tessier, Katelyn M. MacNeil, Joe S. Mymryk
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/9/8/188