A Single Case of Rosai-Dorfman Disease Marked by Pathologic Fractures, Kidney Failure, and Liver Cirrhosis Treated with Single-Agent Cladribine

A Single Case of Rosai-Dorfman Disease Marked by Pathologic Fractures, Kidney Failure, and Liver Cirrhosis Treated with Single-Agent Cladribine

Rosai-Dorfman disease (RDD) is a proliferative histiocytic disorder of unknown etiology which is characterized by sinus histiocytosis with massive lymphadenopathy. In most cases, RDD has a benign course and treatment is not necessary. However, severe cases of RDD require treatment, and the treatment...

Full description

Bibliographic Details
Main Authors: Koji eSasaki, Naveen ePemmaraju, Jason R. Westin, Wei-Lien eWang, Joseph D Khoury, Donald A. Podoloff, Bryan eMoon, Naval eDaver, Gautam eBorthakur
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Oncology
Subjects:
Cladribine
Histiocytes
Rosai-Dorfman disease
CD163
S-100
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00297/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00297/full

Similar Items