HSP90 inhibitor inhibits glycolysis and promotes apoptosis of mouse hepatocarcinoma cell line H22

Objective To investigate the effect of HSP90 inhibitor on glycolysis and apoptosis in mouse hepatocarcinoma cells, and to explore its underlying mechanism. Methods Examine the level of lactate and ATP in mouse hepatoma cell line H22 treated with CORT, GR antagonist RU486 and HSP90 inhibitor 17-AA...

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Bibliographic Details
Main Author: LIU Na-si, CAO Ming-yue, WU You-ming, HUANG Wei, YANG Nan, LIU Yan-yong
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2020-07-01
Series:Jichu yixue yu linchuang
Subjects:
Online Access:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2020-40-7-912.pdf