TP-CSO: A Triptolide Prodrug for Pancreatic Cancer Treatment

Triptolide (TP) is a potential drug candidate for the treatment of cancer, but its use was hampered by its systemic toxicity and poor water solubility. Hence, a TP-CSO prodrug was synthesized by conjugating TP to chitosan oligosaccharide (CSO), and characterized by <sup>1</sup>H NMR, FTI...

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Bibliographic Details
Main Authors: Xinlong Wang, Huahui Zeng, Xin Zhu, Duanjie Xu, Qikang Tian, Can Wang, Lingzhou Zhao, Junwei Zhao, Mingsan Miao, Xiangxiang Wu
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/12/3686