Comparative Molecular Transporter Properties of Cyclic Peptides Containing Tryptophan and Arginine Residues Formed through Disulfide Cyclization

Comparative Molecular Transporter Properties of Cyclic Peptides Containing Tryptophan and Arginine Residues Formed through Disulfide Cyclization

We have previously reported cyclic cell-penetrating peptides [WR]<sub>5</sub> and [WR]<sub>4</sub> as molecular transporters. To optimize further the utility of our developed peptides for targeted therapy in cancer cells using the redox condition, we designed a new generation...

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Bibliographic Details
Main Authors: Eman H. M. Mohammed, Dindyal Mandal, Saghar Mozaffari, Magdy Abdel-Hamied Zahran, Amany Mostafa Osman, Rakesh Kumar Tiwari, Keykavous Parang
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Molecules
Subjects:
cell-penetrating peptide
cancer
cytotoxicity
cellular uptake
disulfide bridge
drug delivery
Online Access:https://www.mdpi.com/1420-3049/25/11/2581

Internet

https://www.mdpi.com/1420-3049/25/11/2581

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