An innovative strategy to identify new targets for delivering antibodies to the brain has led to the exploration of the integrin family

An innovative strategy to identify new targets for delivering antibodies to the brain has led to the exploration of the integrin family

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<h4>Background</h4> Increasing brain exposure of biotherapeutics is key to success in central nervous system disease drug discovery. Accessing the brain parenchyma is especially difficult for large polar molecules such as biotherapeutics and antibodies because of the blood-brain barrier....

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Bibliographic Details
Main Authors: Céline Cegarra, Béatrice Cameron, Catarina Chaves, Tarik Dabdoubi, Tuan-Minh Do, Bruno Genêt, Valérie Roudières, Yi Shi, Patricia Tchepikoff, Dominique Lesuisse
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477330/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477330/?tool=EBI

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