FAM150A and FAM150B are activating ligands for anaplastic lymphoma kinase
Aberrant activation of anaplastic lymphoma kinase (ALK) has been described in a range of human cancers, including non-small cell lung cancer and neuroblastoma (Hallberg and Palmer, 2013). Vertebrate ALK has been considered to be an orphan receptor and the identity of the ALK ligand(s) is a critical...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2015-09-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/09811 |