Molecular imaging of a fluorescent antibody against epidermal growth factor receptor detects high-grade glioma

Abstract The prognosis for high-grade glioma (HGG) remains dismal and the extent of resection correlates with overall survival and progression free disease. Epidermal growth factor receptor (EGFR) is a biomarker heterogeneously expressed in HGG. We assessed the feasibility of detecting HGG using nea...

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Bibliographic Details
Main Authors: Quan Zhou, Johana C. M. Vega Leonel, Michelle Rai Santoso, Christy Wilson, Nynke S. van den Berg, Carmel T. Chan, Muna Aryal, Hannes Vogel, Romain Cayrol, Michael J. Mandella, Frank Schonig, Guolan Lu, Sanjiv S. Gambhir, Michael E. Moseley, Eben L. Rosenthal, Gerald A. Grant
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-84831-4