Tumor microenvironment-responsive spherical nucleic acid nanoparticles for enhanced chemo-immunotherapy

Tumor microenvironment-responsive spherical nucleic acid nanoparticles for enhanced chemo-immunotherapy

Abstract Certain chemotherapeutics can induce tumor cells’ immunogenic cell death (ICD), release tumor antigens, and thereby trigger personalized antitumor immune responses. Co-delivery of adjuvants using nanocarriers could amplify the ICD-induced tumor-specific immunity achieving a synergistic chem...

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Bibliographic Details
Main Authors: Bing Ma, Yingying Ma, Bo Deng, Pengjun Xiao, Pengyu Huang, Dali Wang, Lanxia Liu
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Journal of Nanobiotechnology
Subjects:
Nanoparticle
Self-assembly
Immunotherapy
Anti-tumor immunity
Combination therapy
Online Access:https://doi.org/10.1186/s12951-023-01916-0

Internet

https://doi.org/10.1186/s12951-023-01916-0

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