Utility of 18F-FDG PET with a semi-quantitative index in the detection of sarcomatous transformation in patients with neurofibromatosis type 1.

BACKGROUND: Malignant peripheral nerve sheath tumors (MPNSTs) are a serious complications of neurofibromatosis type 1 associated with poor prognosis and deeper lesions can be difficult to diagnose. 18-FDG PET improves the detection of malignancies. However, the criteria for malignancy, notably the S...

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Bibliographic Details
Main Authors: Patrick Combemale, Laurence Valeyrie-Allanore, Francesco Giammarile, Stephane Pinson, Bernard Guillot, Denis Mariano Goulart, Pierre Wolkenstein, Jean Yves Blay, Thomas Mognetti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3916322?pdf=render