GSK3β Interacts With CRMP2 and Notch1 and Controls T-Cell Motility

GSK3β Interacts With CRMP2 and Notch1 and Controls T-Cell Motility

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The trafficking of T-cells through peripheral tissues and into afferent lymphatic vessels is essential for immune surveillance and an adaptive immune response. Glycogen synthase kinase 3β (GSK3β) is a serine/threonine kinase and regulates numerous cell/tissue-specific functions, including cell survi...

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Bibliographic Details
Main Authors: Mobashar Hussain Urf Turabe Fazil, Praseetha Prasannan, Brandon Han Siang Wong, Amuthavalli Kottaiswamy, Nur Syazwani Binte Mohamed Salim, Siu Kwan Sze, Navin Kumar Verma
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Immunology
Subjects:
GSK3β
NOTCH1
T-lymphocytes
LFA-1
T-cell migration
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.680071/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.680071/full

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