Human Cardiac Progenitor Spheroids Exhibit Enhanced Engraftment Potential.

A major obstacle to an effective myocardium stem cell therapy has always been the delivery and survival of implanted stem cells in the heart. Better engraftment can be achieved if cells are administered as cell aggregates, which maintain their extra-cellular matrix (ECM). We have generated spheroid...

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Bibliographic Details
Main Authors: Francesca Oltolina, Andrea Zamperone, Donato Colangelo, Luca Gregoletto, Simone Reano, Stefano Pietronave, Simone Merlin, Maria Talmon, Eugenio Novelli, Marco Diena, Carmine Nicoletti, Antonio Musarò, Nicoletta Filigheddu, Antonia Follenzi, Maria Prat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4572703?pdf=render