Neuromodulation targets pathological not physiological beta bursts during gait in Parkinson's disease

Neuromodulation targets pathological not physiological beta bursts during gait in Parkinson's disease

Freezing of gait (FOG) is a devastating axial motor symptom in Parkinson's disease (PD) leading to falls, institutionalization, and even death. The response of FOG to dopaminergic medication and deep brain stimulation (DBS) is complex, variable, and yet to be optimized. Fundamental gaps in the...

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Bibliographic Details
Main Authors: Chioma Anidi, Johanna J. O'Day, Ross W. Anderson, Muhammad Furqan Afzal, Judy Syrkin-Nikolau, Anca Velisar, Helen M. Bronte-Stewart
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Neurobiology of Disease
Subjects:
Parkinson's disease
Freezing of gait
Deep brain stimulation
Beta bursts
Subthalamic nucleus
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118305485

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http://www.sciencedirect.com/science/article/pii/S0969996118305485

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