Metabolic Signature of Warburg Effect in Cancer: An Effective and Obligatory Interplay between Nutrient Transporters and Catabolic/Anabolic Pathways to Promote Tumor Growth

Metabolic Signature of Warburg Effect in Cancer: An Effective and Obligatory Interplay between Nutrient Transporters and Catabolic/Anabolic Pathways to Promote Tumor Growth

Aerobic glycolysis in cancer cells, originally observed by Warburg 100 years ago, which involves the production of lactate as the end product of glucose breakdown even in the presence of adequate oxygen, is the foundation for the current interest in the cancer-cell-specific reprograming of metabolic...

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Bibliographic Details
Main Authors: Marilyn Mathew, Nhi T. Nguyen, Yangzom D. Bhutia, Sathish Sivaprakasam, Vadivel Ganapathy
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Cancers
Subjects:
oncogenes
aerobic glycolysis
lactate receptors
nutrient transporters
glutamine addiction
one-carbon metabolism
Online Access:https://www.mdpi.com/2072-6694/16/3/504

Internet

https://www.mdpi.com/2072-6694/16/3/504

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