Intranasal Immunization Using Mannatide as a Novel Adjuvant for an Inactivated Influenza Vaccine and Its Adjuvant Effect Compared with MF59.

Intranasal Immunization Using Mannatide as a Novel Adjuvant for an Inactivated Influenza Vaccine and Its Adjuvant Effect Compared with MF59.

Intranasal vaccination is more potent than parenteral injection for the prevention of influenza. However, because the poor efficiency of antigen uptake across the nasal mucosa is a key issue, immunostimulatory adjuvants are essential for intranasal vaccines. The immunomodulator mannatide or polyacti...

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Bibliographic Details
Main Authors: Shu-Ting Ren, Xue-Mei Zhang, Peng-Fei Sun, Li-Juan Sun, Xue Guo, Tian Tian, Jian Zhang, Qi-Yuan Guo, Xue Li, Li-Jun Guo, Jin Che, Bing Wang, Hui Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0169501&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0169501&type=printable

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