Erythropoietin suppresses osteoblast apoptosis and ameliorates steroid-induced necrosis of the femoral head in rats by inhibition of STAT1-caspase 3 signaling pathway

Erythropoietin suppresses osteoblast apoptosis and ameliorates steroid-induced necrosis of the femoral head in rats by inhibition of STAT1-caspase 3 signaling pathway

Abstract Background Steroid-induced avascular necrosis of the femoral head (SANFH) is characterized by osteoblast apoptosis, leading to a loss of bone structure and impaired hip joint function. It has been demonstrated that erythropoietin (EPO) performs a number of biological roles. Objective We exa...

Full description

Bibliographic Details
Main Authors: Tingwen Cai, Siyuan Chen, Chenghu Wu, Chao Lou, Weidan Wang, Chihao Lin, Hongyi Jiang, Xinxian Xu
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Musculoskeletal Disorders
Subjects:
Erythropoietin
Apoptosis
Necrosis of the femoral head
STAT1-caspase 3
Online Access:https://doi.org/10.1186/s12891-023-07028-y

Internet

https://doi.org/10.1186/s12891-023-07028-y

Similar Items