Multifunctional Nanostructure RAP‐RL Rescues Alzheimer's Cognitive Deficits through Remodeling the Neurovascular Unit

Multifunctional Nanostructure RAP‐RL Rescues Alzheimer's Cognitive Deficits through Remodeling the Neurovascular Unit

Abstract Cerebrovascular dysfunction characterized by the neurovascular unit (NVU) impairment contributes to the pathogenesis of Alzheimer's disease (AD). In this study, a cerebrovascular‐targeting multifunctional lipoprotein‐biomimetic nanostructure (RAP‐RL) constituted with an antagonist pept...

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Bibliographic Details
Main Authors: Qian Zhang, Qingxiang Song, Xiao Gu, Mengna Zheng, Antian Wang, Gan Jiang, Meng Huang, Huan Chen, Yu Qiu, Bin Bo, Shanbao Tong, Rong Shao, Binyin Li, Gang Wang, Hao Wang, Yongbo Hu, Hongzhuan Chen, Xiaoling Gao
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Advanced Science
Subjects:
Alzheimer's disease
cerebrovasculature
multifunctional nanostructure
NVU remodeling
Online Access:https://doi.org/10.1002/advs.202001918

Internet

https://doi.org/10.1002/advs.202001918

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