Altered Levels and Isoforms of Tau and Nuclear Membrane Invaginations in Huntington’s Disease

Since the early reports of neurofibrillary Tau pathology in brains of some Huntington’s disease (HD) patients, mounting evidence of multiple alterations of Tau in HD brain tissue has emerged in recent years. Such Tau alterations range from increased total levels, imbalance of isoforms generated by a...

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Bibliographic Details
Main Authors: Marta Fernández-Nogales, José J. Lucas
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00574/full