Altered Levels and Isoforms of Tau and Nuclear Membrane Invaginations in Huntington’s Disease
Since the early reports of neurofibrillary Tau pathology in brains of some Huntington’s disease (HD) patients, mounting evidence of multiple alterations of Tau in HD brain tissue has emerged in recent years. Such Tau alterations range from increased total levels, imbalance of isoforms generated by a...
Main Authors: | Marta Fernández-Nogales, José J. Lucas |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-01-01
|
Series: | Frontiers in Cellular Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fncel.2019.00574/full |
Similar Items
-
Targeting Tau to Treat Clinical Features of Huntington's Disease
by: Maria Masnata, et al.
Published: (2020-11-01) -
The Fate of Tau Aggregates Between Clearance and Transmission
by: Assel Seitkazina, et al.
Published: (2022-07-01) -
Editorial: Tau Protein: Mechanisms From Health to Degeneration
by: Isabel Lastres-Becker, et al.
Published: (2021-11-01) -
Human Tau Isoforms and Proteolysis for Production of Toxic Tau Fragments in Neurodegeneration
by: Ben Boyarko, et al.
Published: (2021-10-01) -
Tau Secretion: Good and Bad for Neurons
by: Camille Pernègre, et al.
Published: (2019-06-01)