Convergent, functionally independent signaling by mu and delta opioid receptors in hippocampal parvalbumin interneurons

Convergent, functionally independent signaling by mu and delta opioid receptors in hippocampal parvalbumin interneurons

Functional interactions between G protein-coupled receptors are poised to enhance neuronal sensitivity to neuromodulators and therapeutic drugs. Mu and delta opioid receptors (MORs and DORs) can interact when overexpressed in the same cells, but whether co-expression of endogenous MORs and DORs in n...

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Bibliographic Details
Main Authors: Xinyi Jenny He, Janki Patel, Connor E Weiss, Xiang Ma, Brenda L Bloodgood, Matthew R Banghart
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-11-01
Series:eLife
Subjects:
neuropeptide
GPCR
opioid
heteromer
neuromodulation
enkephalin
Online Access:https://elifesciences.org/articles/69746

Internet

https://elifesciences.org/articles/69746

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