Acetylcholine is released in the basolateral amygdala in response to predictors of reward and enhances the learning of cue-reward contingency

Acetylcholine is released in the basolateral amygdala in response to predictors of reward and enhances the learning of cue-reward contingency

The basolateral amygdala (BLA) is critical for associating initially neutral cues with appetitive and aversive stimuli and receives dense neuromodulatory acetylcholine (ACh) projections. We measured BLA ACh signaling and activity of neurons expressing CaMKIIα (a marker for glutamatergic principal ce...

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Bibliographic Details
Main Authors: Richard B Crouse, Kristen Kim, Hannah M Batchelor, Eric M Girardi, Rufina Kamaletdinova, Justin Chan, Prithviraj Rajebhosale, Steven T Pittenger, Lorna W Role, David A Talmage, Miao Jing, Yulong Li, Xiao-Bing Gao, Yann S Mineur, Marina R Picciotto
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-09-01
Series:eLife
Subjects:
cholinergic
reward learning
fiber photometry
optogenetics
grabach3.0
GCaMP
Online Access:https://elifesciences.org/articles/57335

Internet

https://elifesciences.org/articles/57335

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