Left ventricular assist device implantation causes platelet dysfunction and proinflammatory platelet-neutrophil interaction

Left ventricular assist device implantation causes platelet dysfunction and proinflammatory platelet-neutrophil interaction

Blood flow through left ventricular assist devices (LVAD) may induce activation and dysfunction of platelets. Dysfunctional platelets cause coagulation disturbances and form platelet-neutrophil conjugates (PNC), which contribute to inflammatory tissue damage. This prospective observational cohort st...

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Bibliographic Details
Main Authors: Tiago Granja, Harry Magunia, Patricia Schüssel, Claudius Fischer, Thomas Prüfer, David Schibilsky, Lina Serna-Higuita, Hans Peter Wendel, Christian Schlensak, Helene Häberle, Peter Rosenberger, Andreas Straub
Format: Article
Language:English
Published: Taylor & Francis Group 2022-01-01
Series:Platelets
Subjects:
left ventricular assist device
mechanical circulatory support
platelet dysfunction
platelet-leukocyte interaction
systemic inflammation
Online Access:http://dx.doi.org/10.1080/09537104.2020.1859101

Internet

http://dx.doi.org/10.1080/09537104.2020.1859101

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