A primary role for kinin B1 receptor in inflammation, organ damage, and lethal thrombosis in a rat model of septic shock in diabetes

Diabetes mellitus and septic shock increase the incidence of mortality by thrombosis. Although kinin B1 receptor (B1R) is involved in both pathologies, its role in platelet function and thrombosis remains unknown. This study investigates the expression, the inflammatory, and pro-thrombotic effects o...

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Bibliographic Details
Main Authors: N Tidjane, A Hachem, Y Zaid, Y Merhi, L Gaboury, J-P Girolami, R Couture
Format: Article
Language:English
Published: SAGE Publishing 2015-04-01
Series:European Journal of Inflammation
Online Access:https://doi.org/10.1177/1721727X15577736