Exposure to 4-nonylphenol compromises Leydig cell development in pubertal male mice

Exposure to 4-nonylphenol compromises Leydig cell development in pubertal male mice

Exposure to 4-nonyl phenol (4-NP) on Leydig cell (LC) development and function remains poorly understood. We explored the effects of 4-NP on LC development and elucidate the underlying mechanisms. Male (28-day-old) mice received orally 4-NP (0.125, 0.25, and 0.5 mg/kg/day) for 28 days. We found that...

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Bibliographic Details
Main Authors: Shanhui Tao, Zhiang Yao, Huitao Li, Yiyan Wang, Xinyi Qiao, Yang Yu, Yang Li, Yangyang Ning, Ren-shan Ge, Shijun Li
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Ecotoxicology and Environmental Safety
Subjects:
4-nonylphenol
Leydig cell
Apoptosis
ROS
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323011168

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http://www.sciencedirect.com/science/article/pii/S0147651323011168

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