Rtf1 Transcriptionally Regulates Neonatal and Adult Cardiomyocyte Biology

Rtf1 Transcriptionally Regulates Neonatal and Adult Cardiomyocyte Biology

The PAF1 complex component Rtf1 is an RNA Polymerase II-interacting transcription regulatory protein that promotes transcription elongation and the co-transcriptional monoubiquitination of histone 2B. Rtf1 plays an essential role in the specification of cardiac progenitors from the lateral plate mes...

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Bibliographic Details
Main Authors: Adam D. Langenbacher, Fei Lu, Lauren Crisman, Zi Yi Stephanie Huang, Douglas J. Chapski, Thomas M. Vondriska, Yibin Wang, Chen Gao, Jau-Nian Chen
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
cardiomyocyte
heart
Rtf1
PAF1 complex
transcription regulation
Online Access:https://www.mdpi.com/2308-3425/10/5/221

Internet

https://www.mdpi.com/2308-3425/10/5/221

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