Activity modulation of the Escherichia coli F1FO ATP synthase by a designed antimicrobial peptide via cardiolipin sequestering

Activity modulation of the Escherichia coli F1FO ATP synthase by a designed antimicrobial peptide via cardiolipin sequestering

Summary: Most antimicrobial peptides (AMPs) exert their microbicidal activity through membrane permeabilization. The designed AMP EcDBS1R4 has a cryptic mechanism of action involving the membrane hyperpolarization of Escherichia coli, suggesting that EcDBS1R4 may hinder processes involved in membran...

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Bibliographic Details
Main Authors: Marcin Makowski, Víctor G. Almendro-Vedia, Marco M. Domingues, Octavio L. Franco, Iván López-Montero, Manuel N. Melo, Nuno C. Santos
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:iScience
Subjects:
Microbiology
Applied microbiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223010817

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http://www.sciencedirect.com/science/article/pii/S2589004223010817

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