Structure and Oligonucleotide Binding Efficiency of Differently Prepared Click Chemistry-Type DNA Microarray Slides Based on 3-Azidopropyltrimethoxysilane

Structure and Oligonucleotide Binding Efficiency of Differently Prepared Click Chemistry-Type DNA Microarray Slides Based on 3-Azidopropyltrimethoxysilane

The structural characterization of glass slides surface-modified with 3-azidopropyltrimethoxysilane and used for anchoring nucleic acids, resulting in the so-called DNA microarrays, is presented. Depending on the silanization conditions, the slides were found to show different oligonucleotide bindin...

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Bibliographic Details
Main Authors: Emilia Frydrych-Tomczak, Tomasz Ratajczak, Łukasz Kościński, Agnieszka Ranecka, Natalia Michalak, Tadeusz Luciński, Hieronim Maciejewski, Stefan Jurga, Mikołaj Lewandowski, Marcin K. Chmielewski
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Materials
Subjects:
DNA microarrays
click chemistry
organofunctional silanes
surface modification
functional layers
structure
Online Access:https://www.mdpi.com/1996-1944/14/11/2855

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https://www.mdpi.com/1996-1944/14/11/2855

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