Coexpression of HHLA2 and PD-L1 on Tumor Cells Independently Predicts the Survival of Spinal Chordoma Patients

Coexpression of HHLA2 and PD-L1 on Tumor Cells Independently Predicts the Survival of Spinal Chordoma Patients

BackgroundImmunotherapy only achieves efficacy in some cancer patients, and less is known about other immune checkpoint molecules in chordoma. Here, we aimed to determine the expression of PD-L1, HHLA2, B7H3, IDO-1 and Galectin-9 in spinal chordoma and evaluated their association with tumor infiltra...

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Bibliographic Details
Main Authors: Chao Xia, Wei Huang, Yun-Liang Chen, Hai-Bin Fu, Ming Tang, Tao-Lan Zhang, Jing Li, Guo-Hua Lv, Yi-Guo Yan, Zhi-Hua Ouyang, Nvzhao Yao, Cheng Wang, Ming-Xiang Zou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Immunology
Subjects:
spinal chordoma
immune checkpoint molecules
quantitative immunofluorescence
HHLA2
PD-L1
tumor infiltrating lymphocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.797407/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.797407/full

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