A Facile Ugi/Ullmann Cascade Reaction to Access Fused Indazolo-Quinoxaline Derivatives with Potent Anticancer Activity

A Facile Ugi/Ullmann Cascade Reaction to Access Fused Indazolo-Quinoxaline Derivatives with Potent Anticancer Activity

A facile methodology for the construction of a complex heterocycle indazolo-fused quinoxalinone has been developed via an Ugi four-component reaction (U-4CR) followed by an intramolecular Ullmann reaction. The expeditious process features an operationally simple approach, time efficiency, and a broa...

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Bibliographic Details
Main Authors: Yong Li, Liujun He, Hongxia Qin, Yao Liu, Binxin Yang, Zhigang Xu, Donglin Yang
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Molecules
Subjects:
heterocycles
multicomponent reactions (MCRs)
organic synthesis
indazolo-fused quinoxalinone
anticancer activity
Online Access:https://www.mdpi.com/1420-3049/29/2/464

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https://www.mdpi.com/1420-3049/29/2/464

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