Glyceroniosomes for enhanced intestinal absorption of hydrochlorothiazide and lisinopril in their fixed dose combination

Abstract The objective was to investigate the effect of co-administration of hydrochlorothiazide and lisinopril as fixed dose combination on their intestinal absorption. The scope was extended to enhance intestinal absorption of both drugs. In situ rabbit intestinal absorption through the duodenum a...

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Bibliographic Details
Main Authors: Aya R. Elbasuony, Abdelaziz E. Abdelaziz, Eman A. Mazyed, Gamal M. El Maghraby
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-74986-1