Japanese Encephalitis Virus (JEV) NS1′ Enhances the Viral Infection of Dendritic Cells (DCs) and Macrophages in Pig Tonsils

Japanese Encephalitis Virus (JEV) NS1′ Enhances the Viral Infection of Dendritic Cells (DCs) and Macrophages in Pig Tonsils

ABSTRACT Pigs are the amplifying hosts of Japanese encephalitis virus (JEV). Currently, the safe and effective live attenuated vaccine made of JEV strain SA14-14-2, which does not express NS1′, is widely used in humans and domestic animals to prevent JEV infection. In this study, we constructed the...

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Bibliographic Details
Main Authors: Shengda Xie, Junhui Pan, Qiuting Zhang, Ruting Guan, Xingmiao Yang, Xiaoxiao Yang, Zhenjie Liang, Ruibing Cao
Format: Article
Language:English
Published: American Society for Microbiology 2022-08-01
Series:Microbiology Spectrum
Subjects:
JEV
NS1′
pig
tonsil
infection
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01147-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.01147-22

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