An integrative in-silico analysis discloses a novel molecular subset of colorectal cancer possibly eligible for immune checkpoint immunotherapy

An integrative in-silico analysis discloses a novel molecular subset of colorectal cancer possibly eligible for immune checkpoint immunotherapy

Abstract Background Historically, the molecular classification of colorectal cancer (CRC) was based on the global genomic status, which identified microsatellite instability in mismatch repair (MMR) deficient CRC, and chromosomal instability in MMR proficient CRC. With the introduction of immune che...

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Bibliographic Details
Main Authors: Pasquale Sibilio, Francesca Belardinilli, Valerio Licursi, Paola Paci, Giuseppe Giannini
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Biology Direct
Subjects:
Colorectal cancer
Meta-analysis
Immunoinformatics
Multi-omics
Immunotherapy
Online Access:https://doi.org/10.1186/s13062-022-00324-y

Internet

https://doi.org/10.1186/s13062-022-00324-y

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