Overexpression of miR-32 in Chinese hamster ovary cells increases production of Fc-fusion protein

Overexpression of miR-32 in Chinese hamster ovary cells increases production of Fc-fusion protein

Abstract The demand for industrial genetically modified host cells were increased with the growth of the biopharmaceutical market. Numerous studies on improving host cell productivity have shown that altering host cell growth and viability through genetic engineering can increase recombinant protein...

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Bibliographic Details
Main Authors: Masoume Bazaz, Ahmad Adeli, Mohammad Azizi, Morteza Karimipoor, Freidoun Mahboudi, Noushin Davoudi
Format: Article
Language:English
Published: SpringerOpen 2023-05-01
Series:AMB Express
Subjects:
Fc-fusion
miR-32
microRNA
Productivity
CHO cell engineering
Online Access:https://doi.org/10.1186/s13568-023-01540-z

Internet

https://doi.org/10.1186/s13568-023-01540-z

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