High levels of kappa free light chain synthesis predict cognitive decline in relapsing-remitting multiple sclerosis

High levels of kappa free light chain synthesis predict cognitive decline in relapsing-remitting multiple sclerosis

BackgroundEvolving evidence suggests that measurement of cerebrospinal fluid (CSF) kappa free light chain (KFLC) synthesis has high diagnostic sensitivity and specificity for multiple sclerosis (MS), but its prognostic ability is less investigated. The usefulness of KFLC in predicting cognitive impa...

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Bibliographic Details
Main Authors: Igal Rosenstein, Markus Axelsson, Lenka Novakova, Sofia Rasch, Kaj Blennow, Henrik Zetterberg, Jan Lycke
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
multiple sclerosis
kappa free light chains
cognitive impairment (CI)
symbol digit modalities test (SDMT)
biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1106028/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1106028/full

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