Single-nucleus RNA and multiomics in situ pairwise sequencing reveals cellular heterogeneity of the abnormal ligamentum teres in patients with developmental dysplasia of the hip

Single-nucleus RNA and multiomics in situ pairwise sequencing reveals cellular heterogeneity of the abnormal ligamentum teres in patients with developmental dysplasia of the hip

Developmental dysplasia of the hip (DDH) is the most common hip deformity in pediatric orthopedics. One of the common pathological changes in DDH is the thickening and hypertrophy of the ligamentum teres. However, the underlying pathogenic mechanism responsible for these changes remains unclear. Thi...

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Bibliographic Details
Main Authors: Zhenhui Zhao, Chuiqin Fan, Shiyou Wang, Haoyu Wang, Hansheng Deng, Shuaidan Zeng, Shengping Tang, Li Li, Zhu Xiong, Xin Qiu
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Heliyon
Subjects:
Cellular heterogeneity
Developmental dysplasia of the hip
Ligamentum teres
Multiomics in situ pairwise sequencing
Single-nucleus RNA sequencing
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024038349

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http://www.sciencedirect.com/science/article/pii/S2405844024038349

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