Fibronectin extra domain A (FN-EDA) causes glaucomatous trabecular meshwork, retina, and optic nerve damage in mice

Fibronectin extra domain A (FN-EDA) causes glaucomatous trabecular meshwork, retina, and optic nerve damage in mice

Abstract Background Elevated intraocular pressure (IOP) is a major risk factor for the development and progression of primary open angle glaucoma and is due to trabecular meshwork (TM) damage. Here, we investigate the role of an endogenous Toll-like receptor 4 (TLR4) ligand, FN-EDA, in the developme...

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Bibliographic Details
Main Authors: Timur A. Mavlyutov, Justin J. Myrah, Anil K. Chauhan, Yang Liu, Colleen M. McDowell
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Cell & Bioscience
Subjects:
FN-EDA
Trabecular meshwork
Optic nerve
Glaucoma
Online Access:https://doi.org/10.1186/s13578-022-00800-y

Internet

https://doi.org/10.1186/s13578-022-00800-y

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