Differential regulation of the interferon response in systemic lupus erythematosus distinguishes patients of Asian ancestry

Objectives Type I interferon (IFN) plays a role in the pathogenesis of systemic lupus erythematosus (SLE), but insufficient attention has been directed to the differences in IFN responses between ancestral populations. Here, we explored the expression of the interferon gene signatures (IGSs) in SLE...

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Bibliographic Details
Main Authors: Peter E Lipsky, Jinoos Yazdany, Maria Dall'Era, Katherine A Owen, Prathyusha Bachali, Amrie C Grammer, Erika Hubbard, Ian Rector
Format: Article
Language:English
Published: BMJ Publishing Group 2023-07-01
Series:RMD Open
Online Access:https://rmdopen.bmj.com/content/9/3/e003475.full