An exploratory study for tuft cells in the breast and their relevance in triple-negative breast cancer: the possible relationship of SOX9

An exploratory study for tuft cells in the breast and their relevance in triple-negative breast cancer: the possible relationship of SOX9

Abstract Background Breast cancer is highly heterogeneous, suggesting that small but relevant subsets have been under-recognized. Rare and mainly triple-negative breast cancers (TNBCs) were recently found to exhibit tuft cell-like expression profiles, including POU2F3, the tuft cell master regulator...

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Bibliographic Details
Main Authors: Yosuke Yamada, Ronald Simon, Kosuke Iwane, Yuki Nakanishi, Yasuhide Takeuchi, Akihiko Yoshizawa, Masahiro Takada, Masakazu Toi, Hironori Haga, Alexander Marx, Guido Sauter
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Cancer
Subjects:
Breast neoplasms
POU2F3
SOX9
Triple-negative breast neoplasms
Tuft cells
Online Access:https://doi.org/10.1186/s12885-023-10949-5

Internet

https://doi.org/10.1186/s12885-023-10949-5

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