Liquid biopsy in mice bearing colorectal carcinoma xenografts: gateways regulating the levels of circulating tumor DNA (ctDNA) and miRNA (ctmiRNA)

Liquid biopsy in mice bearing colorectal carcinoma xenografts: gateways regulating the levels of circulating tumor DNA (ctDNA) and miRNA (ctmiRNA)

Abstract Background Circulating tumor DNA (ctDNA) and miRNA (ctmiRNA) are promising biomarkers for early tumor diagnosis, prognosis and monitoring, and to predict therapeutic response. However, a clear understanding of the fine control on their circulating levels is still lacking. Methods Three huma...

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Bibliographic Details
Main Authors: Jessica Gasparello, Matteo Allegretti, Elisa Tremante, Enrica Fabbri, Carla Azzurra Amoreo, Paolo Romania, Elisa Melucci, Katia Messana, Monica Borgatti, Patrizio Giacomini, Roberto Gambari, Alessia Finotti
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Colorectal carcinoma
Liquid biopsy
ctDNA
ctmiRNA
Tumor xenotransplants
Online Access:http://link.springer.com/article/10.1186/s13046-018-0788-1

Internet

http://link.springer.com/article/10.1186/s13046-018-0788-1

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