Angiotensin II Induces Aortic Rupture and Dissection in Osteoprotegerin‐Deficient Mice

Angiotensin II Induces Aortic Rupture and Dissection in Osteoprotegerin‐Deficient Mice

Background The biological mechanism of action for osteoprotegerin, a soluble decoy receptor for the receptor activator of nuclear factor‐kappa B ligand in the vascular structure, has not been elucidated. The study aim was to determine if osteoprotegerin affects aortic structural integrity in angiote...

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Bibliographic Details
Main Authors: Toshihiro Tsuruda, Atsushi Yamashita, Misa Otsu, Masanori Koide, Yuko Nakamichi, Yoko Sekita‐Hatakeyama, Kinta Hatakeyama, Taro Funamoto, Etsuo Chosa, Yujiro Asada, Nobuyuki Udagawa, Johji Kato, Kazuo Kitamura
Format: Article
Language:English
Published: Wiley 2022-04-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
aortic dissection
elastin
extracellular matrix
proteoglycan
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.122.025336

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.122.025336

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