A Genome-Wide Association Study Reveals a <i>BDNF</i>-Centered Molecular Network Associated with Alcohol Dependence and Related Clinical Measures

A Genome-Wide Association Study Reveals a <i>BDNF</i>-Centered Molecular Network Associated with Alcohol Dependence and Related Clinical Measures

At least 50% of factors predisposing to alcohol dependence (AD) are genetic and women affected with this disorder present with more psychiatric comorbidities, probably indicating different genetic factors involved. We aimed to run a genome-wide association study (GWAS) followed by a bioinformatic fu...

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Bibliographic Details
Main Authors: Anastasia Levchenko, Sergey Malov, Alexey Antonik, Anastasia Protsvetkina, Kseniya V. Rybakova, Alexander Kanapin, Alexey N. Yakovlev, Anna Y. Nenasteva, Anton E. Nikolishin, Nikolay Cherkasov, Natalia A. Chuprova, Anna S. Blagonravova, Angelica V. Sergeeva, Tatyana V. Zhilyaeva, Maria K. Denisenko, Raul R. Gainetdinov, Alexander O. Kibitov, Evgeny M. Krupitsky
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biomedicines
Subjects:
alcohol dependence
<i>BDNF</i>
comorbidity
gene network
genome-wide association study
sex differences
Online Access:https://www.mdpi.com/2227-9059/10/12/3007

Internet

https://www.mdpi.com/2227-9059/10/12/3007

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